Types of preimplantation embryo Testing (PGT)
Testing on embryos is called Preimplantation Genetic Testing or PGT for short. There are 3 main types of PGT:
PGT-M * for a genetic condition where there is a known risk of passing the condition onto your children. The ‘M’ stands for monogenic or a single gene disorder. An example of this would be Cystic Fibrosis or Sickle Cell Anaemia.
PGT-SR * is for a genetic condition, which is caused by a rearrangement of genetic material on the structures called chromosomes. These are usually known as translocations, which usually cause miscarriages, but can sometimes result in a child with a genetic condition.
PGT-A ** is a test used to count the number of chromosomes in embryos produced during IVF cycles.
In order to perform PGT on embryos, in Vitro Fertilisation (IVF) treatment is needed. IVF is a medical procedure that involves stimulating ovaries to produce eggs, which are collected and mixed with sperm to produce embryos in the laboratory. When embryos reach a specific stage of development an embryologist removes a tiny sample of cells, called a biopsy for PGT. The embryos are frozen while the analysis is carried out. The PGT results identify healthy embryos suitable for transfer to the womb at a later date. A healthy embryo is thawed and replaced into the womb in a frozen embryo transfer cycle so that a pregnancy will hopefully be achieved.
We understand this treatment journey is complex and believe it is important you have all the information and support you need to help understand the benefits and limitations of IVF treatment with PGT. Embryo testing technology is a rapidly developing field and with our experience and professional relationships, we can investigate, explain, advise and support you about the best embryo testing options for your situation. Read more
* PGT-M/PGT-SR was formerly called pre-implantation genetic diagnosis (PGD)
** PGT-A was formerly called Pre-implantation genetic screening (PGS)